Error al instalar

Buenas, cuando le doy a instalar me salta un error 2753 y este es el log que me da:
[1230:0E8C][2018-01-05T20:37:28]i001: Burn v3.10.3.3007, Windows v10.0 (Build 15063: Service Pack 0), path: C:\Users\Javier\AppData\Local\Temp\{14770C9A-C186-4823-A438-7959B663837C}\.cr\PathOfExileInstaller.exe
[1230:0E8C][2018-01-05T20:37:28]i000: Initializing string variable 'InstallFolder' to value '[ProgramFilesFolder]Grinding Gear Games\Path of Exile'
[1230:0E8C][2018-01-05T20:37:28]i009: Command Line: '-burn.clean.room=C:\Users\Javier\Downloads\PathOfExileInstaller.exe -burn.filehandle.attached=628 -burn.filehandle.self=632'
[1230:0E8C][2018-01-05T20:37:28]i000: Setting string variable 'WixBundleOriginalSource' to value 'C:\Users\Javier\Downloads\PathOfExileInstaller.exe'
[1230:0E8C][2018-01-05T20:37:28]i000: Setting string variable 'WixBundleOriginalSourceFolder' to value 'C:\Users\Javier\Downloads\'
[1230:0E8C][2018-01-05T20:37:29]i000: Setting string variable 'WixBundleLog' to value 'C:\Users\Javier\AppData\Local\Temp\Path_of_Exile_20180105203729.log'
[1230:0E8C][2018-01-05T20:37:29]i000: Setting string variable 'WixBundleName' to value 'Path of Exile'
[1230:0E8C][2018-01-05T20:37:29]i000: Setting string variable 'WixBundleManufacturer' to value 'Grinding Gear Games'
[1230:100C][2018-01-05T20:37:29]i000: Setting numeric variable 'WixStdBALanguageId' to value 1033
[1230:100C][2018-01-05T20:37:29]i000: Setting version variable 'WixBundleFileVersion' to value '3.1.1.24806'
[1230:0E8C][2018-01-05T20:37:29]i100: Detect begin, 1 packages
[1230:0E8C][2018-01-05T20:37:29]i103: Detected related package: {90A4562F-D4A1-4B65-906D-41F236CF6902}, scope: PerMachine, version: 3.0.2.20305, language: 1033 operation: MinorUpdate
[1230:0E8C][2018-01-05T20:37:29]i101: Detected package: PathOfExileInstaller.msi, state: Present, cached: None
[1230:0E8C][2018-01-05T20:37:29]i052: Condition 'Installed OR (VersionNT >= v5.1)' evaluates to true.
[1230:0E8C][2018-01-05T20:37:29]i199: Detect complete, result: 0x0
[1230:100C][2018-01-05T20:37:30]i000: Setting numeric variable 'EulaAcceptCheckbox' to value 1
[1230:100C][2018-01-05T20:37:39]i000: Setting string variable 'InstallFolder' to value 'F:\POE'
[1230:100C][2018-01-05T20:37:39]i000: Setting numeric variable 'EulaAcceptCheckbox' to value 1
[1230:0E8C][2018-01-05T20:37:39]i200: Plan begin, 1 packages, action: Install
[1230:0E8C][2018-01-05T20:37:39]i000: Setting string variable 'WixBundleLog_PathOfExileInstaller.msi' to value 'C:\Users\Javier\AppData\Local\Temp\Path_of_Exile_20180105203729_000_PathOfExileInstaller.msi.log'
[1230:0E8C][2018-01-05T20:37:39]i201: Planned package: PathOfExileInstaller.msi, state: Present, default requested: Present, ba requested: Present, execute: MinorUpgrade, rollback: None, cache: Yes, uncache: No, dependency: Register
[1230:0E8C][2018-01-05T20:37:39]i299: Plan complete, result: 0x0
[1230:0E8C][2018-01-05T20:37:39]i300: Apply begin
[1230:0E8C][2018-01-05T20:37:39]i010: Launching elevated engine process.
[1230:0E8C][2018-01-05T20:37:40]i011: Launched elevated engine process.
[1230:0E8C][2018-01-05T20:37:40]i012: Connected to elevated engine.
[1FF8:012C][2018-01-05T20:37:40]i358: Pausing automatic updates.
[1FF8:012C][2018-01-05T20:37:40]i359: Paused automatic updates.
[1FF8:012C][2018-01-05T20:37:40]i360: Creating a system restore point.
[1FF8:012C][2018-01-05T20:37:40]w363: Could not create system restore point, error: 0x80070422. Continuing...
[1FF8:012C][2018-01-05T20:37:40]i370: Session begin, registration key: SOFTWARE\Microsoft\Windows\CurrentVersion\Uninstall\{a2aaa58d-a3d9-4a80-a283-cf8a198d36a5}, options: 0x7, disable resume: No
[1FF8:012C][2018-01-05T20:37:40]i000: Caching bundle from: 'C:\Users\Javier\AppData\Local\Temp\{3D64192C-A6AA-4735-97FC-B9AB79531875}\.be\PathOfExileInstaller.exe' to: 'C:\ProgramData\Package Cache\{a2aaa58d-a3d9-4a80-a283-cf8a198d36a5}\PathOfExileInstaller.exe'
[1FF8:012C][2018-01-05T20:37:40]i320: Registering bundle dependency provider: {a2aaa58d-a3d9-4a80-a283-cf8a198d36a5}, version: 3.1.1.24806
[1FF8:012C][2018-01-05T20:37:40]i371: Updating session, registration key: SOFTWARE\Microsoft\Windows\CurrentVersion\Uninstall\{a2aaa58d-a3d9-4a80-a283-cf8a198d36a5}, resume: Active, restart initiated: No, disable resume: No
[1FF8:1554][2018-01-05T20:37:41]i305: Verified acquired payload: PathOfExileInstaller.msi at path: C:\ProgramData\Package Cache\.unverified\PathOfExileInstaller.msi, moving to: C:\ProgramData\Package Cache\{90A4562F-D4A1-4B65-906D-41F236CF6902}v3.1.1.24806\PathOfExileInstaller.msi.
[1FF8:012C][2018-01-05T20:37:41]i323: Registering package dependency provider: {90A4562F-D4A1-4B65-906D-41F236CF6902}, version: 3.1.1.24806, package: PathOfExileInstaller.msi
[1FF8:012C][2018-01-05T20:37:41]i301: Applying execute package: PathOfExileInstaller.msi, action: MinorUpgrade, path: C:\ProgramData\Package Cache\{90A4562F-D4A1-4B65-906D-41F236CF6902}v3.1.1.24806\PathOfExileInstaller.msi, arguments: ' ALLUSERS="1" ARPSYSTEMCOMPONENT="1" MSIFASTINSTALL="7" INSTALLDIR="F:\POE"'
[1FF8:012C][2018-01-05T20:37:47]e000: Error 0x80070643: Failed to perform minor upgrade of MSI package.
[1FF8:012C][2018-01-05T20:37:47]e000: Error 0x80070643: Failed to execute MSI package.
[1230:0E8C][2018-01-05T20:37:47]e000: Error 0x80070643: Failed to configure per-machine MSI package.
[1230:0E8C][2018-01-05T20:37:47]i319: Applied execute package: PathOfExileInstaller.msi, result: 0x80070643, restart: None
[1230:0E8C][2018-01-05T20:37:47]e000: Error 0x80070643: Failed to execute MSI package.
[1FF8:012C][2018-01-05T20:37:47]i329: Removed package dependency provider: {90A4562F-D4A1-4B65-906D-41F236CF6902}, package: PathOfExileInstaller.msi
[1FF8:012C][2018-01-05T20:37:47]i351: Removing cached package: PathOfExileInstaller.msi, from path: C:\ProgramData\Package Cache\{90A4562F-D4A1-4B65-906D-41F236CF6902}v3.1.1.24806\
[1FF8:012C][2018-01-05T20:37:47]i372: Session end, registration key: SOFTWARE\Microsoft\Windows\CurrentVersion\Uninstall\{a2aaa58d-a3d9-4a80-a283-cf8a198d36a5}, resume: None, restart: None, disable resume: No
[1FF8:012C][2018-01-05T20:37:47]i330: Removed bundle dependency provider: {a2aaa58d-a3d9-4a80-a283-cf8a198d36a5}
[1FF8:012C][2018-01-05T20:37:47]i352: Removing cached bundle: {a2aaa58d-a3d9-4a80-a283-cf8a198d36a5}, from path: C:\ProgramData\Package Cache\{a2aaa58d-a3d9-4a80-a283-cf8a198d36a5}\
[1FF8:012C][2018-01-05T20:37:47]i371: Updating session, registration key: SOFTWARE\Microsoft\Windows\CurrentVersion\Uninstall\{a2aaa58d-a3d9-4a80-a283-cf8a198d36a5}, resume: None, restart initiated: No, disable resume: No
[1230:0E8C][2018-01-05T20:37:47]i399: Apply complete, result: 0x80070643, restart: None, ba requested restart: No


como podria solucionar esto?., he borrado toda la carpeta de archivos temporales y modificado el registro con el comando regsvr32 vbscript.dll y nada...Gracias

Te pongo la solución alternativa al "Error 2753" y "Error 0x80070643":
1. Instala el cliente en otro ordenador (Ojo: solo el cliente, no hace falta que lo parchees).
2. Copia la carpeta que hayas instalado en el ordenador 2 al ordenador 1 en su ruta de destino.
3. Ejecuta el archivo .exe de Path of Exile (si te salta error del archivo "Content.ggpk" alertando de que tienes otra copia del juego ejecutandose cierra el mensaje y ejecuta el .exe como administrador) para que comience a descargar el contenido.

Te recomiendo que borres la carpeta de archivos temporales y de registro antes de la instalación (los comandos introducelos sin comillas).
1.Registro: Tecla windows+R y escribes "regedit". Edición > Buscar: "path of exile" y después de que te encuentre el primer registro y eliminarlo repites: Edición > Buscar siguiente hasta que te diga que no hay resultados que mostrar.

2.Archivos temporales: Tecla windows+R y escribes "%TEMP%".